A pH-responsive nanoprobe for turn-on F-magnetic resonance imaging
We successfully fabricated 19 F magnetic resonance imaging (MRI) nanoprobes by partly replacing the 2-methylimidazolate of the metal organic framework (MOF) matrix ZIF-8, of which the strong 19 F MRI signal displays an interesting pH dependence property, indicating its great potential as a 19 F MRI...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2018-08, Vol.54 (7), p.9853-9856 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | We successfully fabricated
19
F magnetic resonance imaging (MRI) nanoprobes by partly replacing the 2-methylimidazolate of the metal organic framework (MOF) matrix ZIF-8, of which the strong
19
F MRI signal displays an interesting pH dependence property, indicating its great potential as a
19
F MRI contrast agent for stimuli-responsive imaging with high penetration depth and low background.
A pH-responsive MRI nanoprobe was developed by partially replacing organic linkers in ZIF-8, which displays pH-responsive
in vivo
19
F MRI ability. |
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| ISSN: | 1359-7345 1364-548X |
| DOI: | 10.1039/c8cc06129g |