Internalization of the pseudorabies virus macropinocytosis analyzed by quantum dot-based single-virus tracking
With the aid of the single-virus tracking technique and the quantum dot-labeling strategy, the internalization of the pseudorabies virus (PrV) has been visualized in real time. The results demonstrate that macropinocytosis can be considered as a major pathway for PrV entering HeLa cells, which facil...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2018-10, Vol.54 (79), p.11184-11187 |
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| container_issue | 79 |
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| container_title | Chemical communications (Cambridge, England) |
| container_volume | 54 |
| creator | Lv, Cheng Lin, Yi Sun, En-Ze Tang, Bo Ao, Jian Wang, Jia-Jia Zhang, Zhi-Ling Zheng, Zhenhua Wang, Hanzhong Pang, Dai-Wen |
| description | With the aid of the single-virus tracking technique and the quantum dot-labeling strategy, the internalization of the pseudorabies virus (PrV) has been visualized in real time. The results demonstrate that macropinocytosis can be considered as a major pathway for PrV entering HeLa cells, which facilitates the development of therapeutics for virus-triggered diseases.
Utilizing a single-virus tracking technique, the key steps of the PrV entry process were analyzed in detail by real-time monitoring of quantum dot-labeled PrV. |
| doi_str_mv | 10.1039/c8cc05614e |
| format | Article |
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| ispartof | Chemical communications (Cambridge, England), 2018-10, Vol.54 (79), p.11184-11187 |
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| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| title | Internalization of the pseudorabies virus macropinocytosis analyzed by quantum dot-based single-virus tracking |
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