Uracil grafted imine-based covalent organic framework for nucleobase recognition

An imine-based covalent organic framework (COF) decorated in its cavities with uracil groups has shown selective recognition towards adenine in water. These results show how the confinement of the base-pair inside the COF's pores allows a remarkable selective recognition in aqueous media. An im...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2018, Vol.54 (63), p.8729-8732
Hauptverfasser: Royuela, Sergio, García-Garrido, Eduardo, Martín Arroyo, Miguel, Mancheño, María J, Ramos, María M, González-Rodríguez, David, Somoza, Álvaro, Zamora, Félix, Segura, José L
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Sprache:eng
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Zusammenfassung:An imine-based covalent organic framework (COF) decorated in its cavities with uracil groups has shown selective recognition towards adenine in water. These results show how the confinement of the base-pair inside the COF's pores allows a remarkable selective recognition in aqueous media. An imine-based covalent organic framework (COF) decorated in its cavities with uracil groups has shown selective recognition towards adenine in water.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc04346a