Two new quinoline-based regenerable fluorescent probes with AIE characteristics for selective recognition of Cu in aqueous solution and test strips

Two novel highly selective quinoline-based fluorescent probes ( 1 and 2 ) with an aggregation induced emission (AIE) feature have been designed and synthesized for the rapid analysis of Cu 2+ ions in aqueous media and on paper strips with a fluorescence quenching mechanism. Moreover, probes 1 and 2 exhibit excellent sensitivity and anti-interference for Cu 2+ detection, and the detection limits are as low as 1.3 × 10 −8 M and 8.5 × 10 −8 M, respectively, which are much lower than the allowable standard of Cu 2+ (∼20 μM) in drinking water (EPA). More importantly, these two probes were successfully applied for the determination of Cu 2+ in real aqueous samples and fabrication of simple device test strips for rapid and on-site detection of Cu 2+ ions. Interestingly, they can also be regenerated by adding an excess of S 2− . Additionally, the crystallographic structure of probe 1 was confirmed through a single crystal X-ray study. Job's plot analysis and ESI-MS spectroscopic studies reflect the 1 : 1 complexation of the 1 -Cu 2+ and 2 -Cu 2+ complexes. Furthermore, DFT/TDDFT calculations were performed in order to help in understanding the electronic properties of the complexes and the chelation-induced quenching mechanism. Two novel highly selective quinoline-based fluorescent probes with an aggregation induced emission (AIE) feature are used for rapid analysis of Cu 2+ in aqueous media and on paper strips with a fluorescence quenching mechanism.