A promising dual mode SPECT/CT imaging platform based on 99mTc-labeled multifunctional dendrimer-entrapped gold nanoparticlesElectronic supplementary information (ESI) available: Experimental details and additional experimental results. See DOI: 10.1039/c7tb00543a
Multifunctional 99m Tc-labeled dendrimer-entrapped gold nanoparticles ( 99m Tc-Au DENPs) were designed and synthesized. Our results show that the type of surface groups (acetyl or hydroxyl) significantly impact the biodistribution profile of the 99m Tc-Au DENPs, thereby allowing for preferential SPE...
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Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Multifunctional
99m
Tc-labeled dendrimer-entrapped gold nanoparticles (
99m
Tc-Au DENPs) were designed and synthesized. Our results show that the type of surface groups (acetyl or hydroxyl) significantly impact the biodistribution profile of the
99m
Tc-Au DENPs, thereby allowing for preferential SPECT/CT imaging of different organs.
Multifunctional
99m
Tc-labeled dendrimer-entrapped gold nanoparticles modified with different surface groups can be used for preferential SPECT/CT imaging of different organs. |
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ISSN: | 2050-750X 2050-7518 |
DOI: | 10.1039/c7tb00543a |