Selective monophosphorylation of chitosan via phosphorus oxychlorideElectronic supplementary information (ESI) available. See DOI: 10.1039/c7py00123a

Chitosan was selectively monophosphorylated via reaction with phosphorus oxychloride (POCl 3 ) to enhance water solubility while avoiding polyphosphate formation. The use of POCl 3 resulted in negligible product degradation ( i.e. , breakdown of O -glycosidic bonds) even after a 3 d reaction period...

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Hauptverfasser: Suchyta, Dakota J, Soto, Robert J, Schoenfisch, Mark H
Format: Artikel
Sprache:eng
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Zusammenfassung:Chitosan was selectively monophosphorylated via reaction with phosphorus oxychloride (POCl 3 ) to enhance water solubility while avoiding polyphosphate formation. The use of POCl 3 resulted in negligible product degradation ( i.e. , breakdown of O -glycosidic bonds) even after a 3 d reaction period (
ISSN:1759-9954
1759-9962
DOI:10.1039/c7py00123a