Engineered phage nanofibers induce angiogenesisElectronic supplementary information (ESI) available: [Table S1 & S2 and Fig. S1-S3]. See DOI: 10.1039/c7nr03332j

Herein, we exploited a bioinspired M13 bacteriophage as an angiogenic nanofiber for soft tissue engineering applications. We demonstrated that engineered phage nanofibers induce angiogenesis with specific biochemical and topological cues. Specifically, nanofibrous phage structures provided a novel therapeutic platform for stem cell technologies in ischemic diseases. We demonstrated that engineered phage nanofibers induce angiogenesis as an angiogenic and therapeutic biomaterial platform to restore tissues after ischemic injury.