Distal radical migration strategy: an emerging synthetic means

The remote radical migration strategy has gained considerable momentum. During the past three years, we have witnessed the rapid development of sustainable and practical C-C and C-H bond functionalization by means of long-distance 1, n -radical migration ( n = 4, 5, 6) events. Its advent brings our chemical community a new platform to deal with the challenging migration transformations and thus complements the existing ionic-type migration protocols. In this review, the recent achievements in distal radical migration triggered C-C and C-H bond functionalization are summarized. In the past three years, we have witnessed the rapid development of C-C and C-H bond functionalization by means of long-distance radical migration events which bring us a new platform to deal with the challenging C-C and C-H bond functionalization.