Ruthenium-catalysed one-pot regio- and diastereoselective synthesis of pyrrolo[1,2-a]indoles via cascade C-H functionalization/annulationElectronic supplementary information (ESI) available: Experimental procedures and analytical data of the products. CCDC 1567079 (3a) and 1567080 (5a). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7cc06276a
A cascade approach has been developed towards dual C-C bond formation via consecutive C-H functionalization/cyclization giving access to pyrrolo[1,2- a ]indoles in a highly regio- and diastereoselective manner using catalytic [Ru( p -cymene)Cl 2 ] 2 . The methodology was further expanded to attain p...
Gespeichert in:
Hauptverfasser: | , , , , |
---|---|
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | A cascade approach has been developed towards dual C-C bond formation
via
consecutive C-H functionalization/cyclization giving access to pyrrolo[1,2-
a
]indoles in a highly regio- and diastereoselective manner using catalytic [Ru(
p
-cymene)Cl
2
]
2
. The methodology was further expanded to attain pentacyclic structures involving manifold C-C bond creation.
Catalytic, regioselective and diastereoselective synthesis of pyrrolo[1,2-
a
]indoles through a cascade C-H activation and cyclization process. |
---|---|
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c7cc06276a |