Exhaustive Suzuki-Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol estersElectronic supplementary information (ESI) available: Full experimental details, copies of NMR spectra (PDF). See DOI: 10.1039/c7cc00997f

A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinated pyridines. This method facilitates a formal synthesis of normuscopyridine and the rapid assembly of a dumbbell shaped portion of a [2]rotaxane. A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinated pyridines.