New cadinane sesquiterpenoids from the basidiomycetous fungus Pholiota sp.Electronic supplementary information (ESI) available: Experimental procedures, NMR spectra of compounds 1-5. CCDC 861573 and 861574. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6ra22448b

Five new cadinane sesquiterpenoids, pholiotins A-E ( 1-5 ), and three known compounds, 11-hydroxy-1(10)-valencen-2-one ( 6 ), 8,11-dihydroxy-1(10)-eremophilen-2-one ( 7 ) and durgamone ( 8 ), were isolated from the crude extract of Pholiota sp. Their structures were established on the basis of extensive spectroscopic analysis. Their absolute configurations were determined by X-ray diffraction, the Snatzke's method and electronic circular dichroism (ECD) calculations. All isolates were tested for antifungal activity. The basidiomycetous fungus Pholiota sp. produced five new cadinane sesquiterpenoids pholiotins A-E ( 1-5 ). The absolute configurations were determined by X-ray diffraction, the Snatzke's method and electronic circular dichroism (ECD) calculations.