Highly fluorescent cucurbit[8]uril-perylenemonoimide host-guest complexes as efficient fluorescent probes for N-terminal phenylalanine

We report host-guest fluorescent complexes based on cucurbit[8]uril (CB[8]) and water-soluble perylenemonoimide PMI-1 . The fluorescence of CB[8] : PMI-1 complexes reverses after the displacement with other guest molecules and they could serve as selective and sensitive probes for N-terminal phenylalanine peptides. We have developed host-guest fluorescent complexes based on cucurbit[8]uril and a perylenemonoimide for selective and sensitive detection of N-terminal phenylalanine peptides.