A facile and practical copper diacetate mediated, ligand free C-N cross coupling of trivalent organobismuth compounds with amines and N-heteroarenes

In present work, an efficient Cu(OAc) 2 ·H 2 O catalyzed protocol in the absence of any additional ligand has been developed for the N -arylation of amines and nitrogen containing heterocycles using trivalent organobismuth reagents under mild conditions. This protocol tolerates a variety of functional groups on amines and the organobismuth reagent with a high degree of chemoselectivity. In present work, an efficient Cu(OAc) 2 ·H 2 O catalyzed protocol in the absence of any additional ligand has been developed for the N -arylation of amines and nitrogen containing heterocycles using trivalent organobismuth reagents under mild conditions.