Biologically active γ-lactams: synthesis and natural sources
The γ-lactam moiety is present in a large number of natural and non-natural biologically active compounds. The range of biological activities covered by these compounds is very broad. Functionalized γ-lactams are thus of high interest and have great potential in medicinal chemistry. This review prov...
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Veröffentlicht in: | Organic & biomolecular chemistry 2016-11, Vol.14 (43), p.1134-1156 |
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container_title | Organic & biomolecular chemistry |
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creator | Caruano, J Muccioli, G. G Robiette, R |
description | The γ-lactam moiety is present in a large number of natural and non-natural biologically active compounds. The range of biological activities covered by these compounds is very broad. Functionalized γ-lactams are thus of high interest and have great potential in medicinal chemistry. This review provides a description of the title compounds by focusing on their synthesis, natural sources and biological activities.
This review surveys the different synthetic and natural sources of biologically active γ-lactam compounds. |
doi_str_mv | 10.1039/c6ob01349j |
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source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
title | Biologically active γ-lactams: synthesis and natural sources |
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