Palladium-catalyzed β-(hetero)arylation of α,β-unsaturated valerolactamsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob01126h

A method for the palladium-catalyzed arylation of α,β-unsaturated valerolactams is reported. This new protocol provides arylation products in yields up to 95% and is applicable to a wide array of aryl and heteroaryl bromides. The optimization, scope and limitations are described. A method for the palladium-catalyzed arylation of α,β-unsaturated valerolactams is reported.