Palladium-catalyzed paraformaldehyde insertion: a three-component synthesis of benzofuransElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob00198j

An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction. 2-Aroylbenzofurans were prepared from 2-bromophenols, phenacyl bro...

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Hauptverfasser: Cheng, Xiufang, Peng, Yi, Wu, Jun, Deng, Guo-Jun
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Zusammenfassung:An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction. 2-Aroylbenzofurans were prepared from 2-bromophenols, phenacyl bromides and paraformaldehyde under palladium catalysis conditions.
ISSN:1477-0520
1477-0539
DOI:10.1039/c6ob00198j