A highly versatile platform based on geometrically well-defined 3D DNA nanostructures for selective recognition and positioning of multiplex targetsElectronic supplementary information (ESI) available: DNA sequences, gel characterization, AFM and TEM images, and fluorescence measurements. See DOI: 10.1039/c6nr05411k
We develop a versatile recognition system based on 3D triangular-shaped DNA nanotubes by integrating three different aptamer sequences along the three edges. This would allow multiple binding activities to be combined into a single system. The versatility of this nanotube platform can also provide a...
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| creator | Dai, Ziwen Gao, Qi Cheung, Man Ching Leung, Hoi Man Lau, Terrence Chi Kong Sleiman, Hanadi F Lai, King Wai Chiu Lo, Pik Kwan |
| description | We develop a versatile recognition system based on 3D triangular-shaped DNA nanotubes by integrating three different aptamer sequences along the three edges. This would allow multiple binding activities to be combined into a single system. The versatility of this nanotube platform can also provide a framework for spatial orientation and positioning of different aptamer-binding ligands in a 'pea-pod' architecture.
A versatile system based on aptamer-functionalized DNA nanotubes for multiplex recognition and positioning. |
| doi_str_mv | 10.1039/c6nr05411k |
| format | Article |
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| source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| title | A highly versatile platform based on geometrically well-defined 3D DNA nanostructures for selective recognition and positioning of multiplex targetsElectronic supplementary information (ESI) available: DNA sequences, gel characterization, AFM and TEM images, and fluorescence measurements. See DOI: 10.1039/c6nr05411k |
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