Iron-catalyzed carbonylation of aryl halides with arylborons using stoichiometric chloroform as the carbon monoxide sourceElectronic supplementary information (ESI) available. See DOI: 10.1039/c6gc02158a

A general iron-catalyzed carbonylative Suzuki-Miyaura coupling of aryl halides with arylborons is reported, using stoichiometric CHCl 3 as the CO source. The high efficiency, economy, selectivity, and operational simplicity of this transformation make this method a valuable tool in organic synthesis. Importantly, the presented strategy allows effective 13 C labeling simply by using the commercially available 13 C-labeled CHCl 3 . On the basis of the initial mechanistic exploration, an aryl radical intermediate is proposed in the present carbonylation process. The highly effective iron-catalyzed carbonylative Suzuki-Miyaura coupling using stoichiometric chloroform as the CO precursor has been developed.