Enantioselective addition of arylboronic acids to methyl 2-formylbenzoates by using a ruthenium/Me-BIPAM catalyst for synthesis of chiral 3-aryl-isobenzofuranonesElectronic supplementary information (ESI) available. CCDC 1420832. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5ob01661d

Ruthenium/Me-BIPAM-catalyzed asymmetric addition of arylboronic acids to methyl 2-formylbenzoates afforded chiral 3-aryl-isobenzofuranones. [RuCl 2 ( p -cymene)] 2 /Me-BIPAM and RuCl 2 (PPh 3 ) 3 /Me-BIPAM catalyst systems tolerate a variety of functional groups and give high yields with high enantioselectivities. [RuCl 2 (p-cymene)] 2 /Me-BIPAM and RuCl 2 (PPh 3 ) 3 /Me-BIPAM catalyst systems tolerate a variety of functional groups and give high yields with high enantioselectivities.