An ionic liquid catalyzed reusable protocol for one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one under mild conditionsElectronic supplementary information (ESI) available: Scanned spectral data. See DOI: 10.1039/c5nj01545f

An efficient protocol has been developed for the synthesis of 2,3-dihydroquinazolinone compounds from anthranilamide and aldehydes or ketones via ionic liquid catalyzed cyclization reaction. The reaction features high efficiency, shorter reaction duration, mild reaction conditions and inexpensive reagents. The catalyst was recovered and reused. The recyclability of ionic liquid resulted in excellent yields of products without loss of any catalytic activity. This article describes an efficient protocol for the syntheses of 2,3-dihydroquinazolinones. The synthetic utility of this methodology has been demonstrated with 30 different substrates. The reaction showed good functional group tolerance and high levels of catalytic activity.