Click and release: fluoride cleavable linker for mild bioorthogonal separation

Herein, we present a water dispersable, magnetic nanoparticle supported "click and release" system. The cleavable linker has been synthesized by using a strain-promoted copper-free "click" reagent to establish the specific link and a fluoride cleavable silane moiety for mild clea...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (5), p.938-941
Hauptverfasser:	Schneider, Elia M, Zeltner, Martin, Zlateski, Vladimir, Grass, Robert N, Stark, Wendelin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Azides - chemistry Azides - isolation & purification Cattle Chymotrypsin - chemistry Chymotrypsin - isolation & purification Chymotrypsin - metabolism Cleavage Click Chemistry Dyes Enzymes Fluorescent Dyes - chemistry Fluorescent Dyes - isolation & purification Fluorides Fluorides - chemistry Magnetite Nanoparticles - chemistry Nanostructure Organic chemistry Reagents Silanes Silanes - chemistry Water - chemistry
Online-Zugang:	Volltext
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