Azeotropic drying free [18F]FDG synthesis and its application to a lab-on-chip platformElectronic supplementary information (ESI) available: Experimental procedures, analytical data and on-chip experimentals. See DOI: 10.1039/c5cc07106b

A very simple and time-saving cartridge-based drying technique for [ 18 F]fluoride allows for an efficient [ 18 F]FDG synthesis using protic solvents and high water content. This novel method has been adapted to a lab-on-chip synthesis platform mitigating the standard azeotropic drying process and demonstrating a proof of concept towards reduced hardware complexity for such systems. [ 18 F]FDG was prepared using a cartridge-based drying technique for [ 18 F]fluoride. The application to a lab-on-chip platform demonstrates a proof of concept towards reduced hardware complexity.