Cobaltate anion couples terminal dienes with trifluoroacetic anhydride: a direct fluoroacylation of 1,3-dienesElectronic supplementary information (ESI) available. CCDC 991428. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc00743c

Perfluoroketones are useful products and intermediates in medicinal chemistry. Herein, cobalt-mediated fluoroacylation of 1,3-dienes is described using perfluorinated anhydrides such as TFAA. The reaction is thought to proceed through a fluoroacylcobalt reagent formed in situ . Perfluoroacylation of 1,3 dienes can also be performed to attain longer chain perfluorinated ketones. Perfluoroketones are useful products and intermediates in medicinal and materials chemistry.