Systemic gene silencing in plants triggered by fluorescent nanoparticle-delivered double-stranded RNA

A cationic fluorescence nanoparticle efficiently enters plants with high transfection efficacy. Applying a mixture of G2/dsRNA to the model plant, Arabidopsis root, leads to significant reduction in the expression of important developmental genes and results in apparent phenotypes. This study report...

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Veröffentlicht in:Nanoscale 2014-09, Vol.6 (17), p.9965-9969
Hauptverfasser: Jiang, Li, Ding, Lian, He, Bicheng, Shen, Jie, Xu, Zejun, Yin, Meizhen, Zhang, Xiaolan
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Sprache:eng
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Zusammenfassung:A cationic fluorescence nanoparticle efficiently enters plants with high transfection efficacy. Applying a mixture of G2/dsRNA to the model plant, Arabidopsis root, leads to significant reduction in the expression of important developmental genes and results in apparent phenotypes. This study reports a non-viral gene nanocarrier which triggers gene silencing in plants and leads to systemic phenotypes. A cationic fluorescence nanoparticle efficiently enters plants with high transfection efficacy.
ISSN:2040-3364
2040-3372
DOI:10.1039/c4nr03481c