Nitrosyl iron complexes with enhanced NO donating ability: synthesis, structure and properties of a new type of salt with the DNIC cations [Fe(SC(NH2)2)2(NO)2]+Electronic supplementary information (ESI) available. CCDC 1001729 and 1001730. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4nj01693a

Novel nitrosyl iron complexes [Fe(SC(NH 2 ) 2 ) 2 (NO) 2 ] 2 SO 4 ·H 2 O( I ) and [Fe(SC(NH 2 ) 2 ) 2 (NO) 2 ] 2 [Fe 2 (S 2 O 3 ) 2 (NO) 4 ]( II ) have been synthesized via the reactions of FeSO 4 and Na 2 [Fe 2 (S 2 O 3 ) 2 (NO) 4 ], respectively, with acidic solutions of thiocarbamide in water. The structure and properties of I and II were studied using X-ray analysis, Mössbauer, IR, and EPR spectroscopy and amperometry. Both complexes are characterized by a prolonged NO generation without additional activation in aqueous anaerobic solutions, similar to the organic NO donor diethylene triamine; however, they are more effective: at pH 7 the NO amount is ∼32.6 and ∼31.8 nM mol −1 of the complex for I and II , respectively. The obtained results show feasibility for the synthesis of water-soluble hybrid nitrosyl NO-generating complexes, which contain the NO groups both in the cationic and anionic sublattices and provide the control of the NO release kinetics. A new structural type of water-soluble iron nitrosyl complexes with thiocarbamide has been obtained.