Specific oxyfunctionalisations catalysed by peroxygenases: opportunities, challenges and solutions

Peroxygenases enable H 2 O 2 -driven oxyfunctionalisation of organic compounds such as selective epoxidation, hydroxylation and heteroatom oxygenation. Therefore, peroxygenases are potentially very useful tools for the organic chemist. This contribution reviews the current state of the art in peroxygenases, their availability, engineering and reaction scope. Current challenges and possible solutions are critically discussed. Peroxygenases are promising oxyfunctionalisation catalysts for organic synthesis.