Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labelingThis work is dedicated to the memory of Elizabeth A. Jares-Erijman.Electronic supplementary information (ESI) available: Reagents and instruments, synthetic and labeling procedures, additional spectroscopic data, 1H, 13CNMR, and HRMS. See DOI: 10.1039/c4cc10425k

This work describes a novel mono-boronic acid derivative of a tricarbocyanine. The probe is a genuine near-infrared fluorescence emitter with improved properties such as a large Stokes shift, excellent water solubility and sensitive fluorogenicity upon binding to carbohydrates under physiological conditions. The detection performance in solution and in live cells of a novel mono-boronic acid derivative of a near-infrared luminescent tricarbocyanine with OFF-ON response upon addition of saccharides.