Photocontrolled chignolin-derived β-hairpin peptidomimeticsElectronic supplementary information (ESI) available: Experimental procedures, analytical data and selected spectra of all new compounds. See DOI: 10.1039/c4cc10304a

The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy. The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported.