A simple modular aptasensor platform utilizing cucurbit[7]uril and a ferrocene derivative as an ultrastable supramolecular linkerElectronic supplementary information (ESI) available: Experimental details of chemical synthesis, SPR measurements and filter binding assays. See DOI: 10.1039/c4cc08027k

A simple modular aptamer-based sensor (aptasensor) platform was prepared by combining the merits of the rapid and efficient preparation of a self-assembled monolayer of cucurbit[7]uril (CB[7] SAM) and the strong and specific binding affinity of CB[7] to ferrocenemethylammonium (FA), as an ultrastabl...

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Hauptverfasser: Lee, Don-Wook, Park, Kyeng Min, Gong, Bokyoung, Shetty, Dinesh, Khedkar, Jayshree K, Baek, Kangkyun, Kim, Jeehong, Ryu, Sung Ho, Kim, Kimoon
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Sprache:eng
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Zusammenfassung:A simple modular aptamer-based sensor (aptasensor) platform was prepared by combining the merits of the rapid and efficient preparation of a self-assembled monolayer of cucurbit[7]uril (CB[7] SAM) and the strong and specific binding affinity of CB[7] to ferrocenemethylammonium (FA), as an ultrastable supramolecular linker, to immobilize aptamers on CB[7] SAM. A simple aptasensor platform was prepared by combining the merits of the efficient preparation of self-assembled monolayer of cucurbit[7]uril and its high binding affinity to ferrocene derivatives.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc08027k