Switching an O2 sensitive glucose oxidase bioelectrode into an almost insensitive one by cofactor redesignElectronic supplementary information (ESI) available: Production and purification of the differents enzymes. See DOI: 10.1039/c4cc01670j

In the 5-8 mM glucose concentration range, of particular interest for diabetes management, glucose oxidase bioelectrodes are O 2 dependent, which decrease their efficiencies. By replacing the natural cofactor of glucose oxidase, we succeeded in turning an O 2 sensitive bioelectrode into an almost insensitive one. We switched an O 2 sensitive glucose oxidase bioelectrode into an almost insensitive one by cofactor redesign.