Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynesElectronic supplementary information (ESI) available. CCDC 993171. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4cc00939h

A palladium-catalyzed one-pot method for the synthesis of quinolines from commercial or readily available 2-amino aromatic ketones and alkynes is reported for the first time. This transformation offers an alternative method for the synthesis of polysubstituted quinoline. A palladium-catalyzed one-pot method for the synthesis of quinolines from commercial or readily available 2-amino aromatic ketones and alkynes is reported for the first time.