Enantio-differentiation of O-heterocycles using a binol-derived disulfonimide as a chiral solvating agentElectronic supplementary information (ESI) available. See DOI: 10.1039/c4cc00466c

The disulfonimide ( R )- 1 enables enantio-differentiation of a large scope of chiral O -heterocycles, thanks to the formation of diastereomeric adducts. The underlying H-bond has been investigated by NMR. ( R )- 1 has been used as a chiral solvating agent (CSA) to determine the stereochemical purity of d / l lactide by 1 H NMR. The disulfonimide ( R )- 1 enables enantio-differentiation of d- and l -lactides, thanks to the formation of diastereomeric H-bond adducts. Such chiral recognition operates with a large scope of ROP monomers and is readily monitored by 1 H NMR spectroscopy.