Asymmetric autocatalysis triggered by oxygen isotopically chiral glycerinElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ob40293b
Chiral ( S )- and ( R )- 18 O-glycerin induces enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, and the subsequent asymmetric autocatalysis affords ( R )- and ( S )-pyrimidyl alkanol with high enantiomeric excess, respectively. Oxygen isotopic ( 18 O/ 16 O) chirality of gly...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Chiral (
S
)- and (
R
)-
18
O-glycerin induces enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, and the subsequent asymmetric autocatalysis affords (
R
)- and (
S
)-pyrimidyl alkanol with high enantiomeric excess, respectively.
Oxygen isotopic (
18
O/
16
O) chirality of glycerin induces enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde with high enantiomeric excess in conjunction with asymmetric autocatalysis. |
|---|---|
| ISSN: | 1477-0520 1477-0539 |
| DOI: | 10.1039/c3ob40293b |