Aerobic oxidation of isosorbide and isomannide employing TEMPO/laccaseElectronic supplementary information (ESI) available: Analytics, sources of chemical and enzymes, computational details. See DOI: 10.1039/c3gc41855c

The oxidation of the renewable diols isosorbide and isomannide was successfully achieved using a TEMPO/laccase system. Furthermore, various TEMPO-derivatives were tested leading to conversions of up to >99% for the oxidation of isosorbide, isomannide, indanol and a halohydrin to the corresponding ketone. sec -Alcohols such as isosorbide were oxidised to the corresponding ketone with >99% conversion.