Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell dropletsElectronic supplementary information (ESI) available. See DOI: 10.1039/c2lc21266h

We constructed a mesh-grid integrated microwell array which enables easy trapping and consistent addition of droplets. The grid acts as a microchannel structure to guide droplets into the microwells underneath, and also provides open access for additional manipulation in a high-throughput manner. Ea...

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Hauptverfasser: Um, Eujin, Rha, Eugene, Choi, Su-Lim, Lee, Seung-Goo, Park, Je-Kyun
Format: Artikel
Sprache:eng
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Zusammenfassung:We constructed a mesh-grid integrated microwell array which enables easy trapping and consistent addition of droplets. The grid acts as a microchannel structure to guide droplets into the microwells underneath, and also provides open access for additional manipulation in a high-throughput manner. Each droplet in the array forms a stable environment of pico-litre volume to implement a single-cell-based assay. A single-cell-based assay is demonstrated using a mesh-integrated microwell array which enables easy trapping and consistent addition of droplets in a high-throughput manner.
ISSN:1473-0197
1473-0189
DOI:10.1039/c2lc21266h