Novel transformation of α,β-unsaturated aldehydes and ketones into γ-amino alcohols or 1,3-oxazines via a 4 or 5 step, one-pot sequenceElectronic supplementary information (ESI) available: Experimental details, characterisation data, ReactIR, 1H and 13C NMR and crystallographic data in CIF format. CCDC 896882. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c2cc36129a

An efficient, 4-step, one-pot, highly stereoselective route to γ-amino alcohols has been developed via an in situ α,β-unsaturated imine formation, β-boration, reduction (C&z.dbd;N) and oxidation (C-B) sequence and especially for certain water-soluble γ-amino alcohols, a further step can be added to directly access the corresponding 1,3-oxazine derivatives. An efficient, 4-step, one-pot, highly stereoselective route to γ-amino alcohols has been developed via an in situ α,β-unsaturated imine formation, β-boration, reduction (C&z.dbd;N) and oxidation (C-B) sequence and for water-soluble products, a further step directly accesses 1,3-oxazine derivatives.