Control of framework interpenetration for in situ modified hydroxyl functionalised IRMOFsThis article is part of the ChemComm 'Metal-organic frameworks' web themed issue.Electronic supplementary information (ESI) available: Synthesis of H2L1, H2L1Ac, H2L1iBu, and H2L2; synthetic details and activation conditions for the MOFs; 1H NMR digestion studies; TGA and EDS data; and crystal data and refinement details for [Zn4O(L1)3] and α-[Zn4O(L2)3]. CCDC 831356 and 831357. For ESI and crystallographic

By intimate control of reaction conditions, phase-pure crystalline porous metal-organic framework materials [Zn 4 O( L ) 3 ] with interpenetrated and non-interpenetrated structures can be synthesised. Under certain conditions, these reactions occur with concomitant deprotection of masked alcohols located on the organic links which yield accessible 'metal-binding' functional groups within the frameworks. Phase-pure metal-organic frameworks [Zn 4 O( L ) 3 ] are formed in one-pot reactions with liberation of accessible 'metal-binding' groups within the frameworks.