A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolinesElectronic supplementary information (ESI) available: Experimental procedure, 1H and 13C NMR spectra for all compounds. CCDC 885176. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c2cc35235d
1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of -amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH 2 Cl 2 . This methodology was utilized to synthesize 2-benzoyl quinolines. 1,1-Cyclopropane aminoketones have been synthesize...
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Sprache: | eng |
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Zusammenfassung: | 1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of -amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH
2
Cl
2
. This methodology was utilized to synthesize 2-benzoyl quinolines.
1,1-Cyclopropane aminoketones have been synthesized from vinyl sulfonium and -amino aryl ketones, subsequent transformations lead to 2-benzoyl quinolines. |
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ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c2cc35235d |