In silico design, synthesis and evaluation of 3-O-benzylated analogs of salacinol, a potent -glucosidase inhibitor isolated from an Ayurvedic traditional medicine "Salacia"Electronic supplementary information (ESI) available: Experimental procedures for 7k and 13k, and their 1H and 13C NMR spectra. See DOI: 10.1039/c2cc34144a

With the aid of an in silico method, -glucosidase inhibitors with far more potent activities than salacinol ( 1 ), a potent natural -glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata , have been developed. With the aid of an in silico method, -glucosidase inhibitors ( 7 ) with far more potent activities than salacinol ( 1 ), a potent natural -glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata , have been developed.