Deep cavitand vesicles - multicompartmental hostsElectronic supplementary information (ESI) available: Experimental procedures, characterization of new compounds, 1H NMR spectra, additional TEM images, fluorescence spectra. See DOI: 10.1039/c2cc34065h

The synthesis and characterization of vesicles assembled from deep cavitands in water is reported. These vesicles act as hosts for three different types of guests: the cavitands bind small guest molecules, the bilayer attracts larger hydrophobic guests and the inner aqueous compartment contains hydrophilic molecules. The formation of vesicles from an amphiphilic deep cavitand and their ability to bind three different kinds of guest molecules are described.