Facile, rapid and efficient biofabrication of gold nanoparticles decorated with functional proteinsElectronic supplementary information (ESI) available. See DOI: 10.1039/c2an35172b

Facile, rapid and efficient biofabrication of gold nanoparticles decorated with functional proteinsElectronic supplementary information (ESI) available. See DOI: 10.1039/c2an35172b

We report a one-pot biological approach to fabricate gold nanoparticle (AuNP)-ZZ domain conjugates using peptide-functionalized proteins that can simultaneously direct both biomineralization and surface modification of AuNPs. In addition, immuno-AuNPs are readily prepared through the specific bindin...

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Hauptverfasser: Shimojo, Kojiro, Niide, Teppei, Taguchi, Tomitsugu, Naganawa, Hirochika, Kamiya, Noriho, Goto, Masahiro
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creator Shimojo, Kojiro
Niide, Teppei
Taguchi, Tomitsugu
Naganawa, Hirochika
Kamiya, Noriho
Goto, Masahiro
description We report a one-pot biological approach to fabricate gold nanoparticle (AuNP)-ZZ domain conjugates using peptide-functionalized proteins that can simultaneously direct both biomineralization and surface modification of AuNPs. In addition, immuno-AuNPs are readily prepared through the specific binding of antibodies to the ZZ domain on the AuNPs. We have developed a simple one-pot strategy to fabricate highly stabilized, monodisperse gold nanoparticle-protein conjugates that can be readily derivatized with antibodies.
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title Facile, rapid and efficient biofabrication of gold nanoparticles decorated with functional proteinsElectronic supplementary information (ESI) available. See DOI: 10.1039/c2an35172b
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