Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reactionElectronic supplementary information (ESI) available. See DOI: 10.1039/c1ob06429k

An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed. Single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides by using a one-pot gold-mediated three-component coupling reaction.