CF2-Containing acetylenephosphonates in heterocyclization reactions: the first synthesis of 2-difluoromethyl azaxanth-3-ylphosphonatesElectronic supplementary information (ESI) available: Experimental details and copies of 1H, 13C, 19F, 31P NMR and MS (HRMS) spectra of new compounds. See DOI: 10.1039/c1ob06379k

Acetylenephosphonates carrying the XCF 2 group have been studied in a base-mediated heterocyclization reaction with selected 2-amino-3-formylchromones to give 2-difluoromethyl azaxanth-3-ylphosphonates. The presence of the fluorinated substituent determined the regioselectivity as well as the reactivity of this process. Acetylenephosphonates carrying the XCF 2 group have been studied in a base-mediated heterocyclization reaction with selected 2-amino-3-formylchromones to give 2-difluoromethyl azaxanth-3-ylphosphonates. The presence of the fluorinated substituent determined the regioselectivity as well as the reactivity of this process.