Tin-free radical reactions under minimal solvent conditions for the synthesis of substituted chromones and coumarinsElectronic supplementary information (ESI) available: Experimental procedures and the NMR spectra for all of the products. See DOI: 10.1039/c1gc15775bA typical experimental procedure (Table 3): To 3-cyanochromone (0.2 mmol) in a 10 mL vial was added alkyl iodide (1.2 mmol) and the reaction initiated using 1.0 M Et3B in THF (0.4 mmol). The reaction mixture turned yellow after the ad

An alkyltin-free radical methodology carried out under minimal solvent conditions is presented. This free radical addition process allows for the preparation of a variety of substrates, including substituted chromones and coumarins. This method is high yielding, conducted at ambient temperature and, in nearly all instances, classical purification techniques such as chromatography are not needed. An alkyltin-free radical methodology for the preparation of substituted chromones and coumarins under minimal solvent conditions is presented.