Copper(i) iodide complexes containing new aliphatic aminophosphine ligands and diimines-luminescent properties and antibacterial activityCCDC reference numbers 747837 (1), 747838 (3P·0.5[Cu2I2(phen)2]), 747839 (3), 747840 (1P·C6H5CH3) and 747841 (2). For crystallographic data in CIF or other electronic format see DOI: 10.1039/b9nj00636b

The new, water soluble, aminomethylphosphines were synthesized from P(CH 2 OH) 3 and alkylpiperazines: P(CH 2 N(CH 2 CH 2 ) 2 NCH 3 ) 3 ( 1 ) and P(CH 2 N(CH 2 CH 2 ) 2 NCH 2 CH 3 ) 3 ( 2 ). Described already in literature P(CH 2 N(CH 2 CH 2 ) 2 O) 3 ( 3 ) were also obtained. The spectroscopic 1 H, 31 P and 13 C NMR analyses and crystallographic studies of 1 , 2 and 3 demonstrate that all these compounds have similar structures and spectroscopic properties, which almost do not depend on aliphatic rings in the molecules. Heteroleptic copper( i ) iodide complexes with phosphines mentioned above and 2,2′-bipyridine (bpy): [CuI(bpy)P(CH 2 N(CH 2 CH 2 ) 2 NCH 3 ) 3 ] ( 1B ), [CuI(bpy)P(CH 2 N(CH 2 CH 2 ) 2 NCH 2 CH 3 ) 3 ] ( 2B ), [CuI(bpy)P(CH 2 N(CH 2 CH 2 ) 2 O) 3 ] ( 3B ) or 1,10-phenanthroline (phen): [CuI(phen)P(CH 2 N(CH 2 CH 2 ) 2 NCH 3 ) 3 ] ( 1P ), [CuI(phen)P(CH 2 N(CH 2 CH 2 )NCH 2 CH 3 ) 3 ] ( 2P ), [CuI(phen)P(CH 2 N(CH 2 CH 2 ) 2 O) 3 ] ( 3P ) were also synthesized. All complexes were characterized by 1 H, 31 P and 13 C NMR spectroscopy also. Molecular structures of 1P ·PhCH 3 and 3P ·0.5Cu 2 I 2 (phen) 2 were determined from single crystal X-ray diffraction studies. Upon excitation at 470 nm, all complexes in the solid state exhibit red photoluminescence due to charge transfer transition. The luminescence of phen complexes is higher than the luminescence of bpy ones. The presented phosphines and copper( i ) complexes were screened for their in vitro antibacterial and antifungal activity against Escherichia coli , Pseudomonas aeruginosa , Staphylococcus aureus strains and Candida albicans . All the copper complexes exhibit significant antibacterial activity against Staphylococcus aureus strains. The activity of 1,10-phenanthroline complexes is higher than 2,2′-bipyridine complexes. Reactions of copper( i ) iodide with diimine ligands and new tris(aminomethyl)phosphines derived from alkylpiperazines and morpholine result in complexes that show antimicrobial activity and solid state photoluminescent properties.