Serum fibrinopeptide A is increased in patients with acute coronary syndrome

Acute coronary syndrome (ACS) is one of the leading causes of mortality, globally. Atherosclerosis is an underlying factor in ACS process and coagulative cascade is activated secondary to atherosclerotic plaque rupture. Fibrinopeptide A (FPA) takes an active role in thrombus formation and is an indi...

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Veröffentlicht in:Northern Clinics of Istanbul 2023-01, Vol.10 (1), p.17-23
Hauptverfasser: Yilmaz, Ahmet Seyda, Uslu, Abdulkadir, Kara, Faruk, Kahraman, Fatih, Cirakoglu, Omer Faruk
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Sprache:eng
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Zusammenfassung:Acute coronary syndrome (ACS) is one of the leading causes of mortality, globally. Atherosclerosis is an underlying factor in ACS process and coagulative cascade is activated secondary to atherosclerotic plaque rupture. Fibrinopeptide A (FPA) takes an active role in thrombus formation and is an indicator of coagulative process. We aimed to evaluate serum FPA level in patients with ACS. Patients diagnosed with ACS and chronic coronary syndrome (CCS), with non-obstructive coronary artery disease as a control group, were included in the study. Blood samples and demographic data of all patients were obtained at admission. Obtained data were compared between ACS and control groups. The study consisted of 107 patients with ACS and 69 patients with CCS. ACS group was older (p
ISSN:2148-4902
2536-4553
DOI:10.14744/nci.2021.12499