What Makes a Useful "Predictor" of Risk for Suicide Attempt?

Barch et al discuss the study by Lee et al which examined whether polygenic risk scores (PRSs) for adult suicide are associated with childhood suicidal ideation and/or attempts, whether this relationship is independent from associations with PRSs for depression and attention-deficit/hyperactivity disorder (ADHD), and what mental health or behavioral factors might mediate the association between adult suicide PRSs and child suicide ideation or behaviors. There were several crucial findings from this study. First, PRSs for adult suicide were associated with child suicide attempts, but not ideation. Second, this association with adult suicide PRSs was over and above shared variance with PRSs for depression and ADHD.