A large A(H3N2) influenza outbreak with a high attack rate in a drug user community in Italy, April 2022

Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. O...

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Veröffentlicht in:	Epidemiology and infection 2023-01, Vol.151, p.e36-e36, Article e36
Hauptverfasser:	Gori, Maria, Fappani, Clara, Bianchi, Silvia, Canuti, Marta, Colzani, Daniela, Ottogalli, Paolo, Duehren, Sarah, Tanzi, Elisabetta, Amendola, Antonella, Boschini, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Bakeries Catering Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 vaccines Disease Outbreaks Disease transmission Drug Users Epidemics Fever From the Field Genetic analysis Genetic drift HIV Human immunodeficiency virus Humans Immunization Incidence Influenza Influenza A Virus, H3N2 Subtype Influenza Vaccines Influenza, Human - epidemiology Italy Outbreaks Pandemics Phylogenetics Public health Rehabilitation Seasons Severe acute respiratory syndrome coronavirus 2 Vaccines Viruses
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Zusammenfassung:	Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. One hundred eighty-four individuals presented influenza-like symptoms (attack rate of 26.2%); 56% previously received the influenza vaccine. Sequence analyses highlighted a genetic drift from the vaccine strain, which may have caused the observed lack of protection.
ISSN:	0950-2688 1469-4409
DOI:	10.1017/S0950268823000055