Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2–10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduct...
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Veröffentlicht in: | International journal of surgery case reports 2023-03, Vol.104, p.107911, Article 107911 |
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Sprache: | eng |
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Zusammenfassung: | Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2–10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities.
In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position.
The use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves.
This clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach.
•Ankylosing spondylitis is a chronic rheumatic disease that can affect heart valves.•Heart damage usually manifests as aortic insufficiency and conduction abnormalities.•Duration of Bekhterev's disease associated with the occurrence of aortic regurgitation.•The use of homografts and autologous materials allow avoid anticoagulants. |
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ISSN: | 2210-2612 2210-2612 |
DOI: | 10.1016/j.ijscr.2023.107911 |