Changes in Acupuncture-Induced Specific Acupoint Neurotransmitters are Possibly Related to Their Physiological Functions in Rats

Changes in Acupuncture-Induced Specific Acupoint Neurotransmitters are Possibly Related to Their Physiological Functions in Rats

This study investigated changes in neurotransmitters induced by the application of electroacupuncture (EA) at Zusanli (ST36) and Neiguan (PC6). A total of 30 rats were divided into five groups: sham, ST (EA at bilateral ST36 and ST37), ScT (ST plus previous neurectomy of the bilateral sciatic nerves...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2023, Vol.2023 (1), p.4849528-4849528
Hauptverfasser: Nguyen, Huong Thi Mai, Lee, Der-Yen, Liu, Chung-Hsiang, Hsieh, Ching-Liang
Format: Artikel
Sprache:eng
Schlagworte:
Acupuncture
Adenosine
Analgesics
Cerebral cortex
Cerebrospinal fluid
Chromatography
Discriminant analysis
Hypothalamus
Laboratory animals
Mass spectrometry
Nerves
Neurotransmitters
Norepinephrine
Physiology
Rodents
Sciatic nerve
Scientific imaging
Spinal cord
γ-Aminobutyric acid
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Zusammenfassung:This study investigated changes in neurotransmitters induced by the application of electroacupuncture (EA) at Zusanli (ST36) and Neiguan (PC6). A total of 30 rats were divided into five groups: sham, ST (EA at bilateral ST36 and ST37), ScT (ST plus previous neurectomy of the bilateral sciatic nerves), ScS (sham plus previous neurectomy of the bilateral sciatic nerve), and PC (EA at bilateral PC6 and PC7). The P2X2 receptor expression was stronger in the sham group than in the ST and PC groups (both p0.05. Dopamine levels in the extracellular fluid surrounding the acupoints were higher in the PC group than in the sham and ST groups during the postacupuncture period (both p
ISSN:1741-427X
1741-4288
DOI:10.1155/2023/4849528